Buscar
Mostrando ítems 1-10 de 3211
Functional RNA Elements in the Dengue Virus Genome
(Molecular Diversity Preservation International, 2011-09-15)
Dengue virus (DENV) genome amplification is a process that involves the viral RNA, cellular and viral proteins, and a complex architecture of cellular membranes. The viral RNA is not a passive template during this process; ...
Genome cyclization as strategy for flavivirus RNA replication
(Elsevier Science, 2008-09)
Long-range and local RNA-RNA contacts in viral RNA genomes result in tertiary structures that modulate the function of enhancers, promoters, and silencers during translation, RNA replication, and encapsidation. In the case ...
A balance between circular and linear forms of the dengue virus genome is crucial for viral replication
(Cold Spring Harbor Laboratory Press, 2010-12)
The plasticity of viral plus strand RNA genomes is fundamental for the multiple functions of these molecules. Local and long-range RNA - RNA interactions provide the scaffold for interacting proteins of the translation, ...
Exploring RNA Virus Replication in Xenopus Oocytes
(Humana Press, 2006)
Microinjection of poliovirus RNA in Xenopus oocytes initiates a complete and authentic viral replication cycle that yields newly synthesized infectious virus. This system can be used to study the molecular mechanism of the ...
Dynamic RNA structures in the dengue virus genome
(Landes Bioscience, 2011)
Dengue virus is an important human pathogen that belongs to the Flaviviridae family. The viral genome is a single molecule of RNA of positive polarity that plays multiple roles during the viral life cycle. Besides encoding ...
Flaviviruses
(Springer, 2009)
Flavivirus genome amplification is a complex process that involves the viral RNA, cellular and viral proteins, and a sophisticated architecture of cellular membranes induced by viral infection. The viral RNA is not just a ...
Inhibition of hepatitis C virus using siRNA targeted to the virus and Hsp90
(2017-01-01)
Hepatitis C (HCV) is a viral disease affecting millions of people worldwide, and persistent HCV infection can lead to progressive liver disease with the development of liver cirrhosis and hepatocellular carcinoma. During ...